Calculate the standard error given specific parameters
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Entering edit mode
8.2 years ago
rednalf ▴ 90

Given the following informations:

CHR1        Variant 1 chromosome code
SNP1        Variant 1 identifier
CHR2        Variant 2 chromosome code
SNP2        Variant 2 identifier
BETA_INT    Regression coefficient (QT)
STAT        Chi-square statistic
DF          Chi-square degrees of freedom
P           Chi-square p-value

Is it correct to calculate the Standard error by dividing "BETA_INT" by "STAT"? And if yes, does the Standard error always have to be positive?

Thank you for your help!

statistics plink standard-error • 1.6k views
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Entering edit mode
8.2 years ago

I think you don't have to divide by STAT, but by the corresponding z-score. Just transform your P to z-score; this link http://sampson.byu.edu/courses/z2p2z-calculator.html is very helpful.

Cheers

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