Find transcription factors that bind to inputted nucleotide sequence?
5
2
Entering edit mode
8.2 years ago

Hello,

Is there a tool where you input a nucleotide sequence, and the tool outputs which transcription factors bind to that sequence?

Thank you

transcription factor • 3.1k views
ADD COMMENT
3
Entering edit mode
8.2 years ago
UnivStudent ▴ 440

I'd recommend the "Scan single sequences for TF binding" tool in CIS-BP using TFs from whatever species you're interested in, or TFs that you're interested in and added to your cart. Alternatively, FIMO is a popular tool from the MEME suite that can be used online, or run on the command line.

ADD COMMENT
2
Entering edit mode
8.2 years ago

HOMER is the best tool I have used so far in terms of ease and good documentation , let me know if you need any help with it : http://homer.salk.edu/homer/index.html

ADD COMMENT
2
Entering edit mode
8.2 years ago
Farbod ★ 3.4k

Dear randalljellis, Hi.

"Catalog of Inferred Sequence Binding Preferences" would be a choice as it Scan a DNA sequence for potential binding sites and can Compare a given motif to all TFs in the database.

http://cisbp.ccbr.utoronto.ca/TFTools.php

ADD COMMENT
1
Entering edit mode
8.2 years ago
EagleEye 7.6k

Try MEME suite,

http://meme-suite.org/index.html

ADD COMMENT
1
Entering edit mode
8.2 years ago

Thank you all so much! I don't know what I would do without this community. I upvoted all of you :)

ADD COMMENT
1
Entering edit mode

I believe that we all are in the same boat !

ADD REPLY

Login before adding your answer.

Traffic: 2512 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6