Generate gene correlation network from mirna data

Question

[carlos_marchi]

Hello guys,

I would like to generate a gene correlation network where the data is mirna expression.

To help in this process , I have the mirna-genes targets data. However, I checked these data and I was able to observe that there are some mirna for a gene, thus how can a gene bind to a specific miRNA or vice-versa?

About the network correlation , I'm using spearman correlation where the correlations above 0.8 are 1 and below 0.8 is 0 in the correlation matrix.

Does anyone have an idea to proceed this?

Thank you very much.

[Lluís R.]

For network correlation have a look on WGCNA.