Estimating tumor purity from genomic data

Question

[Pappu]

I am trying to estimate tumor purity from genomic data. I am wondering which method is good since there are several methods out there.

[GouthamAtla]

what "genomics data" do you have ?

[Pappu]

I got mutation and copy number data.

[John]

I'd imagine this is an incredibly difficult job unless you have single-cell data. Going for a slightly different protocol would be infinitely better than spending an extra year on the data analysis.

Answer 1

[Ron]

CLONET : to infer tumor DNA purity and tumor ploidy

http://demichelislab.unitn.it/doku.php?id=public:clonet