How to calculate power calculations for 450K methylation array data

Question

[shocker8786]

I'm working on an experimental design in which I need to calculate power calculations for detecting differential methylation across 2 groups using the 450K methylation array. I have experience with Illumina sequence data, but not methylation array data. Is it possible to perform a power calculation without any pre-existing data to get an estimate of the number of samples I need to have for each comparison? Any insights would be greatly appreciated. Thanks!

Answer 1

[Neilfws]

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