Good book about sampling/experimental design
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8.0 years ago
TimK ▴ 10

Hi,

Hope this is not too off-topic but I thought I might not be the only bioinf that has to help designing sequencing experiments/workflows. I'm looking for a good book about experimental design with focus on sampling design, e.g. choose sampling sites, controls, replicates etc. Numerical Ecology (Legendre) already gives some advise on dependent and autocorrelation but I'd like to know more about the actual design, what to avoid and why.

Any suggestions? Tim

sequencing • 1.1k views
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Perhaps add which field you are interested in or working in? I assume the book would be quite different if you are sequencing soil bacteria in South America vs dementia patients in Antwerp.

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Hi Wouter,

Thanks for your reply. I'm more interested in environmental sampling and eDNA. However, I would assume that a "good" book should cover many different sampling designs from various environments (in this context I consider the human body also an environment).

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