Is there a database or programmatic way to browse the literature available related to a specific cytoband? Ex: Search "6p22.1" and get a list of papers of research within that cytoband. Something more specific than PubMed, Google, etc.
Would this work well for you? Basically it is a data mining on abstracts (and some free text) available on Medline/Pubmed where the cytoband was extracted. Just select the band and it will give you a list of documents attached to that band. You can even filter by the type of "concept" you want.
You can try our tool http://www.text2genome.org, click browse, click Homo sapiens under UCSC, go to your cytoband and look at the papers.
Text2genome.org is extracting DNA sequences from articles and mapping them to the genome, so it is less applicable for GWAS studies but quite good if you interested in detailed analysis of regions. I am happy about any feedback, by the way.
The paper on Pubmatrix provides an example of how to search all cytobands for specific terms (see results in figure 4), which might be modified to suit your needs.
Very interesting question, following the integration of genes and proteins(GeneRIF, GeneWiki, iHOP and several commercial solutions) with literature next focus should be integration of chromosomal locations locations with literature. This is more relevant as more and more non-coding locations are reported from GWAS studies.
I am not aware of a tool which can handle this at one go, but if you are specifically interested in non-coding regions which are recently reported in GWAS studies GWASIntegrator will be a good start. Here is the result for your query from GWASIntegrator. If your region of interest includes any known genes, you may get the known genes in the area and look for their GeneRIF.
Perhaps MarkerInfoFinder provides the functionality you are looking for, at least for single cytoband queries using a web interface: http://brainarray.mbni.med.umich.edu/brainarray/datamining/MarkerInfoFinder/
See more here: http://www.ncbi.nlm.nih.gov/sites/entrez/17823133
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version 2.3.6
That's a nice tool.