Conservation score calculation for gene sequences

Question

[muvinika]

Please suggest me some tools to calculate Conservation scores. Can we do it bu using Bioedit?

Answer 1

[hns]

Not sure about your workflow. But one good score is CADD

http://cadd.gs.washington.edu/

Thank you

Answer 2

[Alex Reynolds]

PHAST offers phastCons and phyloP methods.