What You Call "Coding Region" On Ensembl Variation

Question

[fetus0000]

Hello, and I have a question regarding GWAS catalog (https://www.ebi.ac.uk/gwas/ ). From this dataset, How can I distinguish those SNPs are in coding region or non-coding region?

I mean that Is it ok in general to understand that variants in "coding-region" is equal to variants in orange regions of the picture from: http://asia.ensembl.org/info/genome/variation/predicted_data.html?

(i.e. You guys refer to variants in coding regions as :synonymous, missense, inframe insertion, inframe deletion, stop gained, frameshift, coding sequence variant?)

Thanks in advance.

[GenoMax]

The variants are classified in GWAS catalog under the "Functional class" column and you have already found the help page for those classes. Is there an unanswered question here?

[fetus0000]

i am sorry, but i want to know the common sense of what you guys scientist call coding regions, is my understanding collect, you think?

[GenoMax]

From original post:

I mean that Is it ok in general to understand that variants in "coding-region" is equal to variants in orange regions

Ensembl glossary defines CDS/coding sequence as

The portion of a gene or an mRNA that codes for a protein. Introns are not coding sequences, nor are the 5' or 3' UTR. The coding sequence in a cDNA or mature mRNA includes everything from the start codon through to the stop codon, inclusive.

[WouterDeCoster]

Assuming you are not from a biology background, coding means that the DNA directly codes for a protein, essentially the DNA is transcribed and translated to protein.

(Ignoring the semantic discussion of "is UTR coding or not" for the sake of simplicity)

[fetus0000]

I'm new to this kind, and thank you very much for those answers. I really appreciate that. But I still don't clearly understand, a bit confused. I attached a picture of my thinking, is this correct, you think?

[GenoMax]

Variants in red box will have an effect (not always deleterious) on the encoded protein. The 4 effects above your red box would also be included in this class.

[fetus0000]

Thank you very much for your kind answer. I finally come to understand, but not fully, and from your view I might be asking a stupid question... The pic attached is I think correct in context of "variants that directly affect encoded protein".