SRR/ERR/DRR prefixes in SRA - What's the difference?
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7.6 years ago
crawforc3 ▴ 60

I couldn't find much in the SRA hand book about the differences between the read prefixes. I am downloading the Tardigrade reads and was just curious (https://www.ncbi.nlm.nih.gov/sra/DRX012456[accn])

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7.6 years ago
lh3 33k

They were submitted to different databases. SRR to NCBI, ERR to EBI and DRR to DDBJ, I believe.

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To expand on this a bit, SRA/ENA/DDBJ sync uploads with each other so people don't have to upload everywhere. Consequently, the accessions numbers will get transferred as well so people can just stick a single accession number in their papers and everyone can then find that in any of the databases.

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Oh cool. That's handy. Thanks!

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So does that mean that all SRR codes have equivalent DRR and ERR codes?

The list I have contains mainly SRR codes, but also ERR and DRR codes. Might they be duplicates? Could it be the same SRA files on different databases?

If that is the case, then I suppose using more than one prefix could ruin my research, no?

Thanks in advance

I see the SRA_Accessions.tab file used to supply data about runs has no ERRs and only a few DRRs, and they do not have GEO accession codes...

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The accession number doesn't change, so you'll find the same SRR (or ERR or DRR) code on SRA, ENA and DDBJ.

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