How can i find the sequence of human domain ?

0

Entering edit mode

7.7 years ago

arta ▴ 670

Hey,

I have done domain enrichment analysis and I got the significantly enriched domains from pfam. Now I would like to find the sequence of domains in human. Further I will align them for certain groups. But I could not find a source or database. Any help will be much appreciated.

domain database alignment • 1.6k views

ADD COMMENT • link 7.7 years ago by arta ▴ 670

0

Entering edit mode

What is a "sequence of domains"?

ADD REPLY • link 7.7 years ago by Matteo Schiavinato ★ 3.6k

0

Entering edit mode

I meant 'protein sequence of domain'.

ADD REPLY • link 7.7 years ago by arta ▴ 670

0

Entering edit mode

Which domain are you referring to?

ADD REPLY • link 7.7 years ago by GenoMax 148k

0

Entering edit mode

There is no specific domain that i am referring. First it should be conserved among other species, (that is why they are called domain), second i have clusters of genes and the domains of the genes should enriched in given cluster. I have the domains for each clusters, now I would like to align them for similarity of sequence or to check signals in the protein sequence. I guess, i was not clear at first. Sorry for that.

ADD REPLY • link 7.7 years ago by arta ▴ 670

1

Entering edit mode

Check out ExPASy.

This sounds like an assignment question. It is still not clear what part of the path you described above you are at.

ADD REPLY • link 7.7 years ago by GenoMax 148k

Login before adding your answer.