Hi,
I have a list of transcripts, such as: ENST00000416191. I want to find the Ensembl IDs for the genes they are associated with. Would I get identical results, whether I query GRCh38 or GRCh37? Note that I am not interested in their coordinates, only the IDs.
Thank you
In general, ensembl IDs do not change between assemblies. A new ID may come in (for eg. new finding) and an existing ID (for eg. deprecation) may disappear. But for an existing entity (gene, contig, transcript etc), IDs do not change between assemblies. This would be same for NCBI, UCSC, EBI, Uniprot etc.
The IDs may stay the same but the information (your entity) they are pointing to can change quite a lot!
Same ENST may point to a
in different builds. Depending on what you are using your ID and the collected data for, this can make a huge difference! Stay carefull and don't expect too much identity in the underlying data, when you search for the same ID in a new database version a few years later.
It is unfortunate that in some case it does change even within the same genome version. Here is one example I have mentioned in my previous post.