Integrate Several Microarray and RNA-Seq Datasets
1
5
Entering edit mode
7.4 years ago
lessismore ★ 1.4k

Although this topic has been discussed in the past in several other occasions, i am curious to know your current opinion about that. Several methods have been proposed and i would know from you how you would deal with combining several microarray and RNA-seq experiments for whatever purpose (DE-analyses, Gene Regulatory Networks, etc..), thus how would you address problems as removing batch effects and transform/normalize the data before processing it.

If you can please cite some relevant paper on that.

Thanks in advance

( 1. Combining Gene Expression Microarray Datasets 2. workflow for combining multiple microarray studies of same platform 3. https://www.researchgate.net/post/How_can_you_combine_different_published_expression_datasets_and_analyze_them_in_R 4. Combining Microarray and RNAseq data 5. methods of integrating microarray data and RNAseq data 6. Is it possible to combine micro array data and RNA-Seq data and perform meta analysis for differential gene expression analysis. 7. Combined Rnaseq + Microarray Transcriptomics Datasets 8. Integrating Different Data Types To Infer Gene Regulatory Networks 9. https://support.bioconductor.org/p/75246/ )

RNA-Seq microarray data integration • 2.1k views
ADD COMMENT
0
Entering edit mode
7.4 years ago
theobroma22 ★ 1.2k

Ultimately, you have to determine the best method by doing all available methods, and use the one that had the best result.

ADD COMMENT

Login before adding your answer.

Traffic: 1724 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6