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Job:Research Officer - Systems Genomics (Melbourne, Australia)

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7.4 years ago

mbrozynska ▴ 50

Two newly created roles, based in Melbourne
Full Time
1 Year contract in the first instance with possibility to extend
Generous Salary Packaging options

About Baker

Baker Heart & Diabetes Institute is an independent, internationally renowned medical research facility. Our work extends from the laboratory to wide-scale community studies with a focus on diagnosis, prevention and treatment of diabetes and cardiovascular disease.

The Baker Institute has a project-oriented environment, encompassing a local and multi-site (including interstate) organisational structure. The staff comprise mainly research, scientific and specialist clinical personnel engaged in the capacity of permanent, grant specific and casual employment. The atmosphere is collegial, usually relaxed and informal though busy and often dynamic with frequent deadlines that must be met. The environment is often demanding and challenging with a strong team orientation but also provides the opportunity to work independently and show initiative. The nature of the work also requires a focus on accuracy and detail.

About the Role

We seek two Research Officers to join our Systems Genomics Lab (Head: A/Prof Michael Inouye)

Systems Genomics is a young and dynamic lab, which primarily operates in a dry (i.e. computational) environment. We aim to alleviate the burden of disease using our interdisciplinary strengths in statistics, computation and bioscience to leverage the latest genomic/biomolecular technologies. We straddle basic and translational research in diseases with strong immune/inflammatory aetiologies, such as cardiovascular disease, asthma and autoimmunity.

By leveraging the immense opportunities of large datasets, the group focuses on:

building genomic risk scores for multi-factorial (complex) diseases then applying them to medicine and public health; and
understanding the systems-level basis for disease through integrative network analysis of genes, metabolites, microbiota and health records.

Duties

In this role you will be expected to:

Build and validate genomic risk scores for common diseases (e.g. autoimmune disorders, cardiovascular diseases, etc)
Investigate the application of genomic risk on clinical or public health scenarios
Provide bioinformatics expertise for experimental/study design, data analyses and interpretation, and reporting of results
Coordinate the processing and analysis of large-scale data
Develop new and/or revised research methodologies
Perform critical analyses of literature relevant to research
Assist in the design and implementation of complex statistical techniques and data processing systems
Organise data, research and analysis procedures

Skills and Experience

You will have:

A PhD, MD, or MBBS with formal training in a quantitative discipline (such as bioinformatics, computational biology, computer science or statistics) and/or health science discipline (such as public health, microbiology, biochemistry, pathology)
Research experience in genetics, genomics, computational biology or bioinformatics including significant experience of computational data analysis and management of large data sets
Experience in statistical analysis of human genomic data with application to genome-wide association studies, genomic risk scores, phenotype prediction or related analyses
A high level of interpersonal skills, excellent oral and written communication skills
Demonstrated ability to lead and participate positively in a team including coordinating activities of students and junior staff
Experience of managing large datasets and establishing analysis pipelines, including those for basic sequence/genomic data quality control and processing
Experience in statistical modeling of genomic or other omic data
Well-developed time management skills, excellent planning and organisational skills
Demonstrated attention to detail and accuracy
Demonstrated ability to use Unix-based systems, compute clusters and related queuing systems, modern scripting/programming languages including R

Benefits

Salary is $79-85K + super and salary packaging, commensurate with the successful candidate's qualifications and experience.

How to Apply

Applications should include a current resume with details of 3 professional referees quoting reference (MI01). To be eligible to apply for this position you must have an appropriate Australian or New Zealand work visa or intend to apply for a valid visa. For a position description or further information, please visit our website at: www.baker.edu.au. We will close this job ad on July 21st or as soon as we have enough applicants so please apply without delay.