Entering edit mode
7.4 years ago
Peavil
▴
10
I am wondering the criteria for denoting unknown data in cosmic db.
for example PIK3CA gene,
Accession Number Gene CDS length HGNC ID Sample name ID_sample ID_tumour Primary site Site subtype 1 Site subtype 2 Site subtype 3 Primary histology Histology subtype 1 Histology subtype 2 Histology subtype 3 Genome-wide screen Mutation ID Mutation CDS Mutation AA Mutation Description
NM_006218.1 3207 8975 2493513 2493513 2356117 breast NS NS NS carcinoma NS NS NS n COSM29325 c.? p.H1047R
NM_006218.1 3207 8975 1670204 1670204 1583490 breast NS NS NS carcinoma NS NS NS n COSM775 c.3140A>G p.H1047R Substitution - Missense
These two data seem to be similar. Even Mutation AA (Amino acid) has the same value(p.H1047R), the below data has the cds number(c.3140A>G), and the above data shows that the cds number is unknown(c.?).
I wonder why I know the "mutation AA information" but the cds information is unknown.