Entering edit mode
7.6 years ago
ghostforever.shi
▴
50
Hi, everyone, I have a problem about the difference between Bowtie and BWA. It is said that BWA first built the suffix array and then generate the BWT. Bowtie use BWT to compress the FM-index. I wonder what's the difference between these two process? Thanks.
I guess the best source of information for your question are the source codes, but not many people are proficient at the level required. It would be a very good exercise, in case you want to further your programming skills. By the way,
bwa
andbowtie
orbowtie2
are far better tags thannext-gen
andalignment
.Oh, I got it, thanks a lot.