Convert drug target data from DrugBank "EB" format to Entrez format?
0
0
Entering edit mode
7.3 years ago

I have extracted data from the DrugBank database (in XML format); this includes the Target ID info available via the path <targets> --> <target> --> <id> value. These data are in the format "BE0000XXX" where X are numerals.

I need to convert these target IDs into Entrez ID format, but first need to determine in which format these "BE" identifiers are. I have reviewed the DrugBank documentation (https://www.drugbank.ca/documentation), which lists Target ID info as GenBank, UniProt, and PDB formats. However, when I searched for some example "BE" identifiers on those three sites, there were no results, indicating that the "BE" format does not correspond to any of these platforms. These identifiers are listed on the DrugBank site. However, the ID conversion tools that I have encountered, such as DAVID, require gene IDs to be supplied, whereas I am not finding tools to convert from a DrugBank target "BE" ID to Entrez ID format.

Ideally, I am seeking to do this in R, but will be happy if I can locate any method to accomplish this.

I will appreciate any clarification about how I might convert my "BE"-type target identifiers from the DrugBank database into Entrez ID format. Thanks in advance for your advice.

conversion DrugBank Entrez • 2.2k views
ADD COMMENT
1
Entering edit mode

Hi, BE is means 'bio entities', is the id of target, you can map the BE id to uniprot id , then to entrez id . for example: BE0000048 maped to uniprot id P00734

ADD REPLY
0
Entering edit mode

Thanks for your clarification and suggestion, Sparrow_kop; that is very helpful.

ADD REPLY

Login before adding your answer.

Traffic: 2670 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6