Downloading the latest human genome

Question

[KVC_bioinfo]

Hello,

I want to download the entire latest human genome for using it as a reference in mapping to RNA-seq data. I am aware that I can do that with the following link: ftp://ftp.ensembl.org/pub/release-90/fasta/homo_sapiens/dna/

However, I want one fasta file with all chromosomes. Is there any way to download it? Or I have to download individually and concatenate it?

Thank you in advance

[GenoMax]

One file from UCSC.

[KVC_bioinfo]

Thank you very much!

[KVC_bioinfo]

This does not give me one file.

[GenoMax]

Link has been updated. Try now.

[4ndrii.v4sylenko]

I can't open ftp://ftp.ensembl.org/pub/realease-90/fasta/homo_sapiens/dna/

[GenoMax]

That is an old release that is no longer available. This is the latest.

Answer 1

[Satyajeet Khare]

Just check the Readme file in the same folder. I guess you need Primary or Toplevel file. Look up for more information in case and decide accordingly.

Answer 2

[tiago211287]

There are many places to download the full human genome, I suggest gencode:

Genome sequence, primary assembly (GRCh38)

Answer 3

[shoujun.gu]

Gencode is my favorite clean and clear