Best Resources For Developmental Biology / Embryology Connected To Bioinformatics

Question

[Samuel Lampa]

I have an MSc in Biotechnology with some basics in Bioinformatics and plan to test some ideas for simulating embryologic development processes, hopefully connected to known gene regulatory networks (GRNs) regulating these processes.

For this purpose, I'm looking for good books or online material to gain the knowledge required. I think I firstly need a foundation in developmental biology so tips on good such books are welcome. Additionally any resources for working with developmental biology in a bioinformatics context is welcome too.

Answer 1

[Mary]

That's kind of a broad question. But I'll give you my favorite mouse resource: http://www.emouseatlas.org/emap/home.html

[Samuel Lampa]

Thanks! The EMAGE software, used in the "Embryo Space" looks very interesting for my use case (I suppose experimental time/space data is very important for verifying (at least 3D-based) simulations...)

[Samuel Lampa]

I'll give you the accept mark for now ... guess these kind of integrative resources are among the better sources ...

Answer 2

[Mikael Huss]

You should definitely check out Eric Davidson's work on GRNs in sea urchin development. See e g http://www.its.caltech.edu/~mirsky/pubs.htm.

[Samuel Lampa]

True. I actually stumbled into his work some time ago and came to read quite some, and I can only agree. Also, AFAIS it's impressive stuff.