literature review by a web server

Question

[niutster]

Hi

Can anybody introduce a web-server to report genes resulted from published papers for a special disease? I need to literature review resulted genes from my research and know any new genes.

Thanks

Answer 1

[GenoMax]

• Open targets platform from EMBL-EBI is your best free option.
• OMIM is focused on mendelian diseases in humans
• Then there are commercial options like Ingenuity Pathway Analysis from Qiagen that require a license purchase.

Answer 2

[Maxime Lamontagne]

IBioGuide could hep you.

Answer 3

[Denise CS]

Building up on one of @genomax' suggestion, i.e. Open Targets. The 17.06 release of the Open Targets Platform shows 2122 targets associated with asthma based on the literature evidence only.

We mine the scientific literature (no reviews, just research articles) and look for the co-occurrence of target and disease (names or symbols, synonyms) in the same sentence. This co-occurence can be in the abstract, title, body of the article (not supplementary materials though). Depending where the sentence lies, we give a stronger or weaker score. This is the text mining evidence for IL17A in asthma. Check the Literature evidence in Open Targets - a target validation platform for the technical details.

You can also use the Open Targets REST API for more advanced queries (we've got a Python client as well). Check Open Targets and programmatic access for the details and/or our API documentation.