Entering edit mode
7.1 years ago
khn
▴
130
Hello,
I am working on HLA imputation using SNP2HLA. I created the files as below. Output Files
{OUTPUT}.dosage
{OUTPUT}.bgl.phased
{OUTPUT}[.bed/.bim/.fam/.ped/.map]
{OUTPUT}.bgl.gprobs
{OUTPUT}.bgl.r2
But how can I get the results as below? Do I need to use additional tools? Otherwise the files above do not give us any specific data for allels or amino acids...
1. Classical HLA alleles: HLA_[GENE]_[ALLELE].
2.HLA Amino Acids: AA_[GENE]_[AMINO ACID POSITION]_[GENETIC POSITION]_[ALLELE].
3.HLA intragenic SNPS: SNP_[GENE]_[POSITION]_[ALLELE] 4.Insertions/deletions:[VARIANT]_[GENE]_[POSITION]_[INSERTION/x=DELETION]
Thank you in advance!