Circos image for Copy Number Variation

Question

[bk11]

Hi,

I am learning circos to make image for my CNV data, however I am not getting image that I wanted. Could any one please help me by sharing the circos.conf script to create circos image using CNV data? I will appreciate your help. Thank you!

Answer 1

[Samarth Kulshrestha]

Hi,

There are different ways of representing data in a circular format (CIRCOS).

http://circos.ca/documentation/tutorials/recipes/copy_number_data/lesson

Go through the link mentioned above, here is one of the tutorials you can plot your CNV values with circos.

Best

[bk11]

I had already tried this tutorial with my data but it did not work. May be I missed some tricks. If you have custom scripts, can you please share? Thanks.

[Samarth Kulshrestha]

Hi,

There are number of published study where CNV tracks have been plotted in a circular fashion using CIRCOS. I strongly suggest you to explore more of genomics research article for your reference. Below is a link of article [for your reference] where authors have generated a CNV frequency plot. I hope this is the kind of data plot you are looking for.

https://doi.org/10.1186/gb-2014-15-4-r55

Best