Genomic Datasets similar to TCGA BRCA and METABRIC

Question

[camclean]

Good afternoon,

I am searching for data sets similar to TCGA BRCA and METABRIC that have cancer genomic data. While both of these sets are for breast cancer, we are interested in discovering genomic patterns common across different cancer sites. My background is Computer Science, so much of the Biology is still quite foreign. I am aware of the TCGA sets on portal.gdc.cancer.gov but I am interested in other resources as well.

Also, if anyone has some insight on the different data types on the TCGA projects, I'd appreciate the clarification. I have an idea but clarifying the following would be very helpful:

• Transcriptome Profiling
• Simple Nucleotide Variation
• Clinical
• Raw Sequencing Data
• Copy Number Variation
• DNA Methylation
• Biospecimen

Answer 1

[timijan]

Hi,

Maybe you can check Human Protein Atlas https://www.proteinatlas.org/? You will not find SNVs but there is information about the level of RNA and protein expression in different cancers as well as tissues.

For somatic variants in cancer there is a database Cosmic, which is free of charge if you are working for a research institution.

[camclean]

Thanks for the suggestion, I'll take a look shortly. I'm with a University so I should hope to get access to most of these things.