Insert size is so small, good or bad?

Question

[Tania]

If you have the average insert size is ~158 estimated using BBMap . While the read length from the fastq file is 150. so we paired reads length (2*150)

This means the paired end reads overlap by too much. Is this good or bad?

[Jingjingzhang]

Bad, the insert size of my some bam files is one or zero. Then, I use the manta to call SV, it failed.

Answer 1

[Sharon]

This is a related good read https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906532/