How to normalize and pool normal human samples?
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7.0 years ago
mittu1602 ▴ 200

I have four healthy samples which are hybridization capture based of targeted regions from Illumnia machine. I need to pool and normalize them to use these samples as "one single control sample" any simpler way to do it. I am learning. Thank you

ngs illumina • 1.4k views
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What kind of analysis are you going to perform? Depth of Coverage?

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Yes and also to use it as a further reference of control sample

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I think there are software packages available to work in this way, such as ExomeCNV

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