Identify Target Genes Of A Pathway

Question

[Rima]

How can I get the list of target genes of a pathway. I want to get the target genes for the wnt signaling pathway using KEGG or DAVID. Or is there any other way to do this ? How do I do that ?

Thanks

[Russh]

so many question marks. Could you describe what you've done so far. Have you looked on the KEGG website?

[Khader Shameer]

What do you mean by target genes, do you mean all genes in a given pathway ?

[Pierre Lindenbaum]

"be nice". I removed all those question marks.

[Russh]

haha, sorry. I'm keen to know if rima would like to work in R or in some other system for the KEGG stuff. I suspect DAVID won't be possible.

[Pierre Lindenbaum]

@russH , the "be nice" was addressed to @rima :-)

[Pi]

DAVID have just released a web service interface for beta testing

Answer 1

[Larry_Parnell]

I have used the KEGG Wnt signaling pathway genes but also like that from NetPath. You can obtain the NetPath Wnt signaling pathway at http://www.netpath.org/pathways?path_id=NetPath_8. The data come via HPRD.

Wnt signaling at KEGG = 149 genes

Wnt signaling at NetPath = 105 genes

64 genes are shared.