Haplotype LD block without genotypes
1
0
Entering edit mode
7.0 years ago

Hi. Is there a tool which can generate haplotype blocks (with plot, like Haploview) without genotype data? I only have a list of SNPs. Thanks!

GWAS Haplotype LD • 2.1k views
ADD COMMENT
0
Entering edit mode

Given that LD is the non-random association of alleles at different loci, I would say: NO! However, if you are working in human and you have a list of SNPs, maybe you can browse the 1000 genome data and see if they share haplotype blocks data (I think they do, but I do not know where).

ADD REPLY
2
Entering edit mode
7.0 years ago

You could use LDLink's LDMatrix and select the appropriate population

https://analysistools.nci.nih.gov/LDlink/?tab=ldhap

ADD COMMENT
0
Entering edit mode

Thanks! It works perfectly. However, is it possible to draw a triangular matrix (since it's symmetric) rather than a square matrix?

ADD REPLY

Login before adding your answer.

Traffic: 1544 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6