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6.9 years ago
virus_n00b
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0
I have a list of sequences (12527). On this, I perform MAFFT to get the sequence alignment in clustal format. FastTree is used to generate the phylogenetic tree from the clustal format file.
Currently, if I encounter a new sequence then the entire procedure is done again to generate the new phylo tree. Is there a method where this procedure can be bypassed partially or fully (by leveraging the previous files i.e sequence aligned file and tree file) to generate the tree.
maftt --addhttps://mafft.cbrc.jp/alignment/software/addsequences.html