indexed human reference genome

Question

[bioinfo355]

Before alignment, bwa is used to create indexes of a genome. I have to use human genome reference seq for alignment. are indexes of human reference genome through bwa available online to download?

Answer 1

[zhenyisong]

iGenomes. The ftp site provides the indexed human genomes for different versions. You can also download the corresponding assembly from NCBI or ENSEMBL or UCSC. And create your own indexed genome using

bwa index -a bwtsw <your genome fasta file>