Software to analyse mutational signatures other than DeconstructSigs R package
1
0
Entering edit mode
6.9 years ago

I am currently researching mutational signatures in Cancer genomes (see here for an explanation: http://cancer.sanger.ac.uk/cosmic/signatures ). I am using the DeconstructSigs package in R to analyze the data I have available. I was just wondering, do there exist other software for performing the same task that are seen as better? I know of the existence of the SomaticSignatures package but am unclear whether it is any better or worse than DeconstructSigs.

Any advice would be greatly appreciated!

R genome cancer mutations • 2.7k views
ADD COMMENT
0
Entering edit mode
6.9 years ago
poisonAlien ★ 3.2k

There are few other tools. DeconstructSigs estimates loading of known signatures for every sample in the cohort. If you are interested in de-novo you could try EMu and Mutational Signature framework. Both from Sanger.

ADD COMMENT

Login before adding your answer.

Traffic: 1530 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6