how to get protparam physico and chemical properties for each sequence using perl programming?

Question

[jananiinfo14]

I have lot of protein sequence in one file. I need protparam physico and chemical prperties for each sequence.how to get the information using perl or any other programming language.

Answer 1

[Elisabeth Gasteiger]

There isn't a very sophisticated way of accessing ProtParam programmatically, but you can send GET requests such as https://web.expasy.org/cgi-bin/protparam/protparam1/?P15457@noft@ (for UniProtKB accession P15457) https://web.expasy.org/cgi-bin/protparam/protparam/?sequence=ASADSDFSF (for raw sequence ASADSDFSF)

If you decide to use this approach, we strongly recommend that you wait for the result of one query before submitting the next one, in order to make responsible use of the server resources. If in doubt, contact the ExPASy helpdesk.