Create a BED restriction digest file in HiC-Pro

Question

[rahman.samir33]

Hi, I am trying to create a BED file in HiCPro containing all the restriction fragments created by DpnII. I have loaded the hg19.fasta file in the annotation folder. When I run the command HiC-Pro_2.10.0/bin/utils/digest_genome.py -r dpnii -o hg19_dpnii.bed hg19.fasta I get the following error message: No such file or directory

What's going wrong? I would appreciate your help.

Answer 1

[Francis]

You can try change the dpnii to DpnII.