How can I calculate and compare intra-cluster correlation for each GO term and pathway?
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6.9 years ago
tfhahn ▴ 50

How can I calculate and compare intra-cluster correlation for each GO term and pathway?

I want for all the genes, which belong to the same GO-term, calculate a similarity score. Each GO term can be considered as a cluster. How do I calculate correlation of the time series trajectories for a group consisting of more than 2 genes? In other words, how can I calculate the correlation within a gene cluster? Which clustering algorithm should I use to infer gene function from time series trajectory similarities? Please provide long preferentially to Python code. I am especially interested in yeast data.

gene • 1.8k views
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Hi Thomas, Kevin here, is this connected to your PhD project? I have received your emails

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Yes. I need this for my dissertation. Could you please help with that? I replied to your email but my reply did not reach you because it came back as not deliverable. Please get in touch with me by voice if you have time.

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I have your email, and Skype messages. We should choose a specific time to call tomorrow. I tried to call you a couple of times in the past but there was no response

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If I could get it published it would count towards the dissertation novelty requirement. If I want I can focus my dissertation on it. When will you call me?

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