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6.8 years ago
jiumeng66
▴
40
Hi, I am trying to convert bed/bim/fam files to vcf file using plink. However, I found that some alleles orders changed. For example, the allele order of rs1877179 in bim file is G/A, but changed to A/G in vcf file. But I need keep the same allele order between bim file and vcf file. I have tried add "--keep-allele-order", but this command did not work. So, what can I do?
PLINK encodes variants as follows:
Are you outputting just a subset of your data, perhaps, in which case the allele frequencies may have changed?