tool to link transcription factors (DEGs) with target genes (DEGs)?

Question

[Muha0216]

Is there an online tool where i can input in all my DEGs and see if there is possible link between transcription factors which were differentially expressed and its target genes which were also differentially expressed?

Answer 1

[GouthamAtla]

You can look at cytoscape apps like iRegulone

I also came across TRRUST recently, which is a database of TF targets.

Keep in mind that TF regulation is very cell type specific and context dependent. The databases are built from data from various cell-types and different cellular context. So check information relevant to the organism / cell type you are working with.