Determining efficient solvents for extracting metabolites

Question

[Natasha]

Hi All,

Is there a way to find out which type of solvent is efficient in extracting polar metabolites and which type of solvent is efficient in extracting non-polar metabolites?

I would like to know whether there are studies that have documented the variation in the solubility of metabolites(in pathways such as glycolysis,TCA cycle, pentose pathway) in different solvents.

[theobroma22]

Water is polar, and Chloroform and methanol are non-polar.

[Natasha]

Thank you very much for the response.I would like to know whether there are studies that have documented the variation in the solubility of metabolites in different solvents.

[theobroma22]

This might be found in reference books; like acetone is a very very strong solvent.