Log2 vs Quantile normalization
0
0
Entering edit mode
6.7 years ago
landscape95 ▴ 190

Hello everyone, I am learning normalizations, I wonder when log2 and quantile normalization is used in each situation, may I ask if there is any material that compare these two types especially in microarray expression matrix for differentially expressed gene analysis? Thank you!

normalization • 3.2k views
ADD COMMENT
0
Entering edit mode

log2 is a transformation rather than a normalization. Are you talking about RNAseq or microarrays or something else entirely?

ADD REPLY
0
Entering edit mode

Yes, I am talking about RNAseq/microarray expression matrix.

ADD REPLY
0
Entering edit mode

Hi landscape95,

It appears that your post has been cross-posted to another site:

https://biology.stackexchange.com/questions/72093/log2-vs-quantile-normalization

This is typically not recommended as it runs the risk of annoying people in both communities. In addition, you cross-posted to an off-topic site, the StackExchange site for bioinformatics is:

https://bioinformatics.stackexchange.com/

ADD REPLY

Login before adding your answer.

Traffic: 1500 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6