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6.6 years ago
nkausthu
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30
Can anyone suggest me the best method to identify common ROH region between two exomes. I have the vcf files for both the samples and I initially used FILTUS but when I cross check FILTUS results manually, I could find heterozygous variants with in the ROH region given by FILTUS. Then I used bcftools but I am not getting proper results. Thanks in advance.
I haven't used it, but the homwes tool in genomecomb developed by our department can find regions of homozygosity, see also the paper.