Target identification of transiption factor
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6.6 years ago
au.rinki.bio ▴ 20

hello Biostar, I have a list of the transcription factor, I want know gene which this transcription factor regulates. kindly suggest me database or tools where I get this type of information. thanking you.

trancription factor • 1.0k views
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6.6 years ago

You could look for ChIP-seq data for your TFs of interest, which would indicate TF binding in gene regulatory regions. Or take the proximal or distal promoter regions of your genes of interest via BEDOPS and run FIMO or other motif discovery tools on those regions to get putative binding sites from your motif models (i.e., TFs) of interest.

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