expected heterozygosity calculation

Question

[Siavash Salek Ardestani]

Hi to all, I have a vcf file that including multisample. I want to calculate expected heterozygosity for this vcf file by sliding-window approach(40-kb-windows slidingin20-kb-steps). I want to know, which software do this? Thanks, Siavash

[trausch]

Number of hets, hom. ref. and hom. alt. in a given region

bcftools stats -r chr1:23000-26000 -s - <input.vcf.gz>

You are probably interested in runs of homozygosity

bcftools roh