Expression Profiles Of Proteins

Question

[Assa Yeroslaviz]

Hi,

can anyone please tell me where I can find a data base of expression profiles for human proteins?

We are working with different human proteins and would like to search for known expression behavior of these proteins.

Is there a data base of protein expression profiles separated into single tissues?

Thanks for any help

A.

[Neilfws]

Do you want to know amount of protein or amount of transcript? The 2 answers given so far seem to assume the latter.

[Casey Bergman]

See related BioStar question here.

[Assa Yeroslaviz]

I would like to know about the protein aboundance in a specific tissue under normal or specific conditions. The problem is that I am not sure if it is possible, without taking the transcript amount into account. But yes, I am interested in the proteins!!!

Answer 1

[Lars Juhl Jensen]

If you are looking for data on which human proteins are expressed in which tissues, I would recommend that you look at the Human Protein Atlas:

http://www.proteinatlas.org/

Answer 2

[Leszek]

I know those:
http://www.ncbi.nlm.nih.gov/geoprofiles/
http://www.genenetwork.org/

[Assa Yeroslaviz]

Is there a way of extracting tissue specific information from the geoprofiles experiments?

Answer 3

[Chris Evelo]

And http://www.ebi.ac.uk/pride/

You could also check: http://www.humanproteinpedia.org/

[Assa Yeroslaviz]

Where are the expression profiles here?

[Chris Evelo]

Looks like you are right, sorry. They only seem to give you the experiment descriptions and the raw and processed identification data. So you can see what was found to be expressed, but not how much. Strange... Anyone knows whether EBI puts the quantitative values somewhere?

[Chris Evelo]

Looks like you are right, sorry. Pride only seems to give you the experiment descriptions and the raw and processed identification data. So you can see what was found to be expressed, but not how much. Strange... Anyone knows whether EBI puts the quantitative values somewhere? I now added another resource.

Answer 4

[Pierre Lindenbaum]

see also http://amazonia.transcriptome.eu/