Clustering 454 amplicon data
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6.6 years ago
Denis ▴ 310

Hi, I'm stuck on 454 amplicons clustering. Because of the indels in homopolymer stretches (etxremely common in this kind of data), one single OTU could be splitted into several ones. Is there any way to optimaze clustering, to count only SNPs not indels during identity culculation?

next-gen sequencing SNP • 945 views
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