Dear all,
I have a question that we use software to call SNP, and get the mutation rate of each SNP, are there any standards to identify if it is a homozygous mutation? like setting a threshold of 40%-80% is heterozygous mutation, and beyond 80% or beneath 40% is homozygous mutation. If there is a international recognized standard?
Thank you for your time.
What you want is an allele frequency threshold.
Mutation rate is the frequency of nucleotide base changes (new mutations) as time passes.