Use Of Terms In Genome-Wide Analysis: Phenotype / Functionality / Fitness

Question

[2184687-1231-83-]

I would like to open a discussion on examples of genome-wide data generation that could be classified into:

• Phenotype measures
• Functionality measures or a proxy for them
• Fitness / changes in fitness

For example:

• Experiment X is a measure for differential phenotypes
• Experiment Y is a proxy for differences in functionality
• Experiment Z is a measure of differences in fitness

What experiments would people consider are good examples for each one?

[Larry_Parnell]

Any reason that fitness, which includes fecundity, fertility, viability, is distinct from phenotype? These three fitness outcomes, while closer to invoking selection than phenotypes in general, are still measurable traits.

[Casey Bergman]

Albert, can you rephrase this more as a proper question?

[Larry_Parnell]

Thank you! That helps. This could be quite a good forum if replies are given for human, animal, Drosophila and plant studies. The ability to perform GWAS in non-human species should not be overlooked.

[2184687-1231-83-]

@Casey Bergman, thanks for the comment, I've now written it down as a question "What experiments would people consider are good examples for each one?"