Merge multiple overlapping consensus sequences

Question

[kspata]

Hi All,

I have 10 consensus sequence files which have some overlapping regions between them. I would like to merge all of them to generate single consensus fasta file. I have looked into emboss merger but it takes only two input files. How can I achieve this? Which software should I use?

Thanks in advance!!!

Answer 1

[GenoMax]

Do a multiple sequence alignment (MSA) with all 10 and then export a consensus. Most MSA programs can be used for this.

[kspata]

Thanks @genomax!!! I used Clustal Omega to align the consensus sequences with each other. Downloaded the JalView results and obtained a consensus sequence.

[GenoMax]

Perfect. So all done then. I will move my comment to an answer that you can accept to provide closure to the thread.