I used co-expression map of a disease obtained from GeneFriends. This map gives information as if a gene is being activated or deactivated. I used it to create Gene Regulatory Network and tried to publish it in journal. They said co-expression maps and GRNs aren't same as GRN have more information including TFs, targets and inhibitory or activatory relationships. Can someone explain the difference in details and can suggest me if no co-expression maps then which RNA-seq data sets I can use to infer GRN. I know about NCBI star and others but they provide raw data set, the first reason to choose data set from GeneFriends was that they provide pre-processed. Does anyone know about other databases like it which can be used?