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6.4 years ago
pengchy
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450
As the title says. I have found that one phenotype transition has more TF genes involved while the reverse process need less TFs. Also, these two processes have different rates of transition. So, I wonder if there was any papers describing the relationship between the number of involved TFs and the rate of phenotype change?
Thank you! Pengcheng
There is a classical example - a sea star and a sea urchin
https://www.sciencedirect.com/science/article/pii/S0012160607013425
Caught in the evolutionary act: Precise cis-regulatory basis of difference in the organization of gene networks of sea stars and sea urchins
As far as I remember, the article describes that TFs working
at different development stages lead to different phenotypes.
I am not sure their amount matter.