Question

Does sciClone work on mouse exome data?

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6.4 years ago

sm.hashemin ▴ 90

Dear people, could I run the sciclone to find subclones from mouse WES data? Best Mo

sciclone clonevol • 1.4k views

ADD COMMENT • link updated 5.5 years ago by Biostar 20 • written 6.4 years ago by sm.hashemin ▴ 90

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It is not a totally absurd idea, take a look https://www.sciencedirect.com/science/article/pii/S2211124717305764 http://cancerimmunolres.aacrjournals.org/content/5/1/29.long

ADD REPLY • link 6.4 years ago by sm.hashemin ▴ 90

score 1 · Answer 1 · 2019-01-15

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5.9 years ago

Chris Miller 22k

I don't see why that wouldn't work, as long as there are enough somatic variants to track from the tumors. (Cluster confidence increases with number of variants and the depth of sequencing).

ADD COMMENT • link 5.9 years ago by Chris Miller 22k