How to interpret ChIP-seq peak at cell line level?
0
0
Entering edit mode
6.4 years ago
Yijun Tian ▴ 20

Hello everyone,

I have a list of enriched peaks called from rigorous prepared ChIP-seq reads obtained by certain treatment which can activate specific transcription factor. The headers are: 1. RegionID 2. chr 3. start 4. end 5. -log10 q-value (QuEST) 6. -log10 p-value (QuEST) 7. Rank 8. ChIP reads 9. High confidence peaks

My question is:

  1. Can we interpret the "Rank" for genomic regions in the list as their affinity to the interest TF across genome.
  2. If yes for question 1, are there any widely accepted models describing the binding order for the interest TF when its concentration or activity gradually increases.

Thanks in advance!

ChIP-Seq • 1.1k views
ADD COMMENT

Login before adding your answer.

Traffic: 2577 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6