Regarding cancer data analysis

Question

[selvasvce]

Hi all,

I have a list of pathways and I want to know the genes that are involved in the particular pathway? For example, let's say vimentin, I wanted to know the list of approved genes in this particular pathway.

I will be glad if you help me

Thanks

[Ram]

What have you tried?

For example, let's say vimentin

What is vimentin? Is it a gene, protein, metabolite or drug? Please show us a little more effort to demonstrate you're invested in this.

[selvasvce]

Hi

it is a structural protein. Vimentin is a type III intermediate filament.

[Ram]

I used Google to find what it is - that's not the point. You should add these details when you create the post. Also, you haven't answered my first question yet - what have you tried?

Answer 1

[GenoMax]

Use Open targets database. Here is an example query with Vimentin.
Similar query at Reactome, Pathway commons.

Answer 2

[EagleEye]

Gene Set Clustering based on Functional annotation (GeneSCF)

With this tool you can retrieve all pathways with corresponding genes for your desired organism as simple text/table format. Example usage here